Introduction to Kubernetes in 2023

The MaiA project codebase is in active development, and the team has finally achieved a continuous integration and continuous deployment workflow. We encountered situations that required the streamlining and automation of some of the frequent, repetitive processes of service updates, scaling, deployment to specific servers (development or stage or production), health checks, monitoring, and so […]

Walkthrough SDTM 3.3 Vs 3.4

In November 2021, the SDTMIG v3.4 and SDTM v2.0 were released. Since 2004, CDISC has provided an accepted standard for the submission of tabulation data in the form of the SDTM and SDTMIG. A large amount of information, as well as new tables, including those for domain specific variables, has been updated to the most […]

Multiplicity in Clinical Trials

The terms pharmacogenomics and pharmacogenetics refer to the study of how a person’s specific genetic sequences influence how they respond to medications. Pharmacogenomics aims to develop reasonable methods for improving therapies in relation to the patient’s genotype in order to achieve maximum effectiveness with the fewest side effects. Pharmacogenomics enables us to identify inter-individual differences […]

An Overview of CDISC Genomic Standards

The terms pharmacogenomics and pharmacogenetics refer to the study of how a person’s specific genetic sequences influence how they respond to medications. Pharmacogenomics aims to develop reasonable methods for improving therapies in relation to the patient’s genotype in order to achieve maximum effectiveness with the fewest side effects. Pharmacogenomics enables us to identify inter-individual differences […]

Clinical Trial Diversity: An Emerging Paradigm in Outcomes Research

Author: Genpro MW & Evidence synthesis team “The enjoyment of the highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition” – Dr Tedros Adhanom Ghebreyesus  Director-General, World Health Organization ‘Right to heath’ and universal health coverage has been […]

CDISC Programming: Importance of Custom Checks

Author: Genpro Statistical Programming Team SDTM-domain structures and relationships are similar across studies under a therapeutic area which leads to code standardization and reusability. Interim data transfers also come with changes in data leading to rerun of existing programs with minor updates. The possibility of errors in such scenarios are large with truncation in data, […]

Artificial Intelligence (AI) Innovations in Clinical Research

Author: Thalla Sanjeeva Reddy – Clinical SAS Programmer at Genpro Introduction Majority of drugs take about 10 years or more to come to market, cost billions, and have a potential to even demolish an organization in certain cases where the late-stage trials fail after having poured in so much speculation. Also, Patients hardly can wait 15 years […]